Respiratory Pathogen Panel (RPP)

Required Documents for RPP Testing:
Helpful Documents for RPP Testing:

COVID-19 and respiratory pathogen panel (RPP) rRT-PCR testing can be performed on a nasopharyngeal swab (NPS). Once collected, the NPS is placed into a specimen tube containing viral transport medium (Hank’s Balanced Salt Solution).

This assay can accurately detect the presence of SARS-CoV-2 virus, as well as various other respiratory pathogens. These two tests can be done individually or together based on the provider’s request.

The COVID-19 test screens for three different SARS-CoV-2-specific genes: the open reading frame (ORF) gene, the envelope (E) gene, and the nucleocapsid (N) gene. A positive result for any of the three genes would indicate the presence of COVID-19 virus. The various targets that can be detected with the respiratory pathogen panel (RPP) assay include influenza A, influenza A H1 [A(H1) and 2009H1N1], influenza A H3, influenza B, respiratory syncytial virus A & B, parainfluenza 1-4, coronavirus 229E, coronavirus NL63, coronavirus OC43, coronavirus HKU1, human metapneumovirus, rhinovirus/enterovirus, adenovirus, human bocavirus, Chlamydophila pneumoniae, and Mycoplasma pneumoniae.

Influenza A, A H1, A H3, 2009 H1N1

Influenza B

Respiratory Syncytial Virus A & B (RSV)

Parainfluenza Virus 1, 2, 3, 4

Human BocavirusHuman Metapneumovirus (hMPV)

Human Rhinovirus/ Enterovirus


Coronavirus HKU1, NL63, OC43, 229ECoViD-19 (ORF, E-gene, and N-gene)

Chlamydophila pneumoniae

Mycoplasma pneumoniae

Viral Targets
Bacterial Targets